カレントテラピー　37-1　サンプル page 11/32

このページは カレントテラピー　37-1　サンプル の電子ブックに掲載されている11ページの概要です。
秒後に電子ブックの対象ページへ移動します。
「電子ブックを開く」をクリックすると今すぐ対象ページへ移動します。

概要：
カレントテラピー　37-1　サンプル

Current Therapy 2019 Vol.37 No.1 21NAFLD/NASHの病態214）He S, McPhaul C, Li JZ, et al：A sequence variation（I148M）in PNPLA3 associated with nonalcoholic fatty liver diseasedisrupts triglyceride hydrolysis. J Biol Chem 285：6706-6715,20105）Kumari M, Schoiswohl G, Chitraju C, et al：Adiponutrin functionsas a nutritionally regulated lysophosphatidic acid acyltransferase.Cell Metab 15：691-702, 20126）Mahdessian H, Taxiarchis A, Popov S, et al：TM6SF2 is aregulator of liver fat metabolism influencing triglyceridesecretion and hepatic lipid droplet content. Proc Natl AcadSci U S A 111：8913-8918, 20147）Dongiovanni P, Petta S, Maglio C, et al：Transmembrane 6superfamily member 2 gene variant disentangles nonalcoholicsteatohepatitis from cardiovascular disease. Hepatology61：506-514, 20158）Cusi K：Role of obesity and lipotoxicity in the developmentof nonalcoholic steatohepatitis：pathophysiology and clinicalimplications. Gastroenterology 142：711-725, 20129）Yamaguchi K, Yang L, McCall S, et al：Inhibiting triglyceridesynthesis improves hepatic steatosis but exacerbatesliver damage and fibrosis in obese mice with nonalcoholicsteatohepatitis. Hepatology 45：1366-1374, 200710）Kubota N, Kubota T, Kajiwara E, et al：Differential hepaticdistribution of insulin receptor substrates causes selectiveinsulin resistance in diabetes and obesity. Nat Commun 7：12977, 201611）Maher JJ, Leon P, Ryan JC：Beyond insulin resistance：innateimmunity in nonalcoholic steatohepatitis. Hepatology 48：670-678, 200812）Imajo K, Fujita K, Yoneda M, et al：Hyperresponsivity tolow-dose endotoxin during progression to nonalcoholic steatohepatitisis regulated by leptin-mediated signaling. CellMetab 16：44-54, 201213）Ikejima K, Takei Y, Honda H, et al：Leptin receptor-mediatedsignaling regulates hepatic fibrogenesis and remodeling ofextracellular matrix in the rat. Gastroenterology 122：1399-1410, 200214）Kamada Y, Tamura S, Kiso S, et al：Enhanced carbon tetrachloride-induced liver fibrosis in mice lacking adiponectin.Gastroenterology 125：1796-1807, 200315）Ley RE, Turnbaugh PJ, Klein S, et al：Microbial ecology：human gut microbes associated with obesity. Nature 444：1022-1023, 200616）Miele L, Valenza V, La Torre G, et al：Increased intestinalpermeability and tight junction alteration in nonalcoholicfatty liver disease. Hepatology 49：1877-1887, 200917）Gao B, Radaeva S, Park O：Liver natural killer and naturalkiller T cells：immunobiology and emerging roles in liverdiseases. J Leukoc Biol 86：513-528, 2009