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カレントテラピー 35-6 サンプル
24 Current Therapy 2017 Vol.35 No.6526きれば,HANDS therapyの適応となり,日常生活での実用性の改善が見込まれる.随意運動が困難な重度片麻痺患者においては,ロボットやBMIの治療の適応となる.手指伸筋群の筋活動が認められない例においてはBMIを用いることにより,手指伸筋群の筋活動の出現を認め,運動機能の改善が得られている.BMIを用いるには皮質運動野が保たれており,ERDの検出がなくてはならない.慢性期重度片麻痺患者では麻痺側上肢の運動イメージが困難であり,ERDの検出が困難な例が存在する.anodal tDCSを用いることにより,重度片麻痺患者においてもERDの増強が可能であり,tDCSとBMIの組み合わせも用いられている21).参考文献1)藤原俊之,阿部 薫:HANDS Therapy.医歯薬出版,東京,20152)日本脳卒中学会 脳卒中ガイドライン委員会:脳卒中治療ガイドライン2015.協和企画,東京,20153)Wolf S, LeCraw DE, Barton LA, et al:Forced use of hemiplegicupper extremities to reverse the effect of learned nonuseamong chronic stroke and head-injured patients. Exp Neurol104:125-132, 19894)Wolf SL, Winstein CJ, Miller JP, et al;EXCITE Investigators:Effect of constraint -induced movement therapy onupper extremity function 3 to 9 months after stroke. TheEXCITE randomized clinical trial. JAMA 296:2095-2104,20065)Dromerick AW, Lang CE, Birkenmeir RL, et al:Very earlyconstraint-induced movement during stroke rehabilitation(VECTORS):A single -center RCT. Neurology 73:195-201, 20096)Fujiwara T, Kawakami M, Honaga K, et al:Hybrid assistiveneuromuscular dynamic stimulation therapy:A new strategyfor improving upper extremity function in patients withhemiparesis following stroke. Neural Plasticity 2350137,5.2017. https://doi.org/10.1155/2017/23501377)de Kroon JR, van der Lee JH, IJzerman MJ, et al:Therapeuticelectrical stimulation to improve motor control and functionalabilities of the upper extremity after stroke:a systematicreview. Clin Rehabil 16:350-360, 20028)Bolton DA, Cauraugh HJ, Hausenblas AH:Electromyogramtriggeredneuromuscular stimulation and stroke motor recoveryof arm/hand functions:a meta -analysis. J Neuro Sci223:121-127, 20049)Khaslavskaia S, Sinkjaer T:Motor cortex excitability followingrepetitive electrical stimulation of the common peronealnerve depends on the voluntary drive. Exp Brain Res 162:497-502, 200510)村岡慶裕,鈴木里砂,島岡秀奉ほか:運動介助型電気刺激装置の開発と脳卒中片麻痺患者への使用経験.理学療法学 31:29-35, 200411)Fujiwara T, Kasashima Y, Honaga K, et al:Motor improvementand corticospinal modulation induced by hybrid assistiveneuromuscular dynamic stimulation(HANDS)therapyin patients with chronic stroke. Neurorehabil Neural Repair23:125-132, 200912)Shindo K, Fujiwara T, Hara J, et al:Effectiveness of HybridAssistive Neuromuscular Dynamic Stimulation Therapy inpatients with subacute stroke:A randomized controlled pilottrial. Neurorehabil Neural Repair 25:830-837, 201113)Fujiwara T, Honaga K, Kawakami M, et al:Modulation ofcortical and spinal inhibition with functional recovery ofupper extremity motor function among patients with chronicstroke. Restor Neurol Neurosci 33:883-894, 201514)Hummel FC, Cohen LG:Non-invasive brain stimulation:anew strategy to improve neurorehabilitation after stroke?Lancet Neurol 5:708-712, 200615)Lotze M, Markert J, Sauseng P, et al:The role of multiplecontralesional motor areas for complex hand movementsafter internal capsular lesion. J Neurosci 26:6096-6102, 200616)Kakuda W, Abo M, Kaito N, et al:Six-day course of repetitivetranscranial magnetic stimulation plus occupational therapyfor post stroke patients with upper limb hemiparesis:acase series study. Disabil Rehabil 32:801-807, 201017)Takeuchi N, Tada T, Toshima M, et al:Repetitive transcranialmagnetic stimulation over bilateral hemispheres enhancesmotor function and training effect of paretic hand inpatients after stroke. J Rehabil Med 41:1049-1054, 200918)Ramos -Murguialday A, Broets D, Rea M, et al:Brain -machine interface in chronic stroke rehabilitation:a controlledstudy. Ann Neurol 74:100-108, 201319)Shindo K, Kawashima K, Ushiba J, et al:Effects of neurofeedbacktraining with an electroencephalogram -basedbrain-computer interface for hand paralysis in patients withchronic stroke:a preliminary case series study. J RehabilMed 43:951-957, 201120)Kawakami M, Fujiwara T, Ushiba J, et al:A new therapeuticapplication of brain -machine interface(BMI)trainingfollowed by hybrid assistive neuromuscular dynamic stimulation(HANDS)therapy for patients with severe hemipareticstroke:A proof of concept study. Restor Neurol Neurosci34:789-797, 201621)Kasashima-Shindo K, Fujiwara T, Ushiba J, et al:Braincomputerinterface training combined with transcranialdirect current stimulation in patients with chronic severehemiparesis:proof of concept study. J Rehabil Med 47:10.2340165019771925, 2015