カレントテラピー 32-4 サンプル

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カレントテラピー 32-4 サンプル

46 Current Therapy 2014 Vol.32 No.4362ルの役割.糖尿病学基礎と臨床. pp74-77, 西村書店, 東京, 20074) Mukai E, Fujimoto S, Sato H, et al:Exendin-4 suppressesSRC activation and reactive oxygen species production indiabetic Goto -Kakizawa rat islets in an Epac -dependentmanner. Diabetes 60:218-226, 20115) Zhang CL, Katoh M, Shibasaki T, et al:The cAMP sensorEpac2 is a direct target of antidiabetic sulfonylurea drugs.Science 325:607-610, 20096) Gutniak M, Orskov C, Holst JJ, et al:Antidiabetogenic effectof glucagon-like peptide-1(7-36)amide in normal subjectsand patients with diabetes mellitus. N Engl J Med 326:1316-1322, 19927) Meier JJ, Gallwitz B, Siepmann N, et al:Gastric inhibitorypolypeptide(GIP)dose -dependently stimulates glucagonsecretion in healthy human subjects at euglycaemia. Diabetologia46:798-801, 20038) Ahren B, Schweizer A, Dejager S, et al:Vildagliptin enhancesislet responsiveness to both hyper- and hypoglycemia inpatients with type 2 diabetes. J Clin Endocrinol Metab 94:1236-1243, 20099) Lambeir AM, Durinx C, Scharpe S, et al:Dipeptidyl-peptidaseⅣ from bench to bedside:an update on structuralproperties, functions, and clinical aspects of the enzymeDPP Ⅳ. Crit Rev Clin Lab Sci 40:209-294, 200310) Holst JJ:The physiology of glucagon-like peptide 1. PhysiolRev 87:1409-1439, 200711) Buse JB, Rosenstock J, Sesti G, et al;LEAD-6 Study Group:Liraglutide once a day versus exenatide twice a day for type2 diabetes:a 26-week randomised, parallel-group, multinational,open-label trial(LEAD-6). Lancet 374:39-47, 200912) Drucker DJ, Buse JB, Taylor K, et al;DURATION-1 StudyGroup:Exenatide once weekly versus twice daily for thetreatment of type 2 diabetes:a randomised, open -label,non-inferiority study. Lancet 372:1240-1250, 200813) Baggio LL, Kim JG, Drucker DJ:Chronic exposure to GLP-1R agonists promotes homologous GLP-1 receptor desensitizationin vitro but does not attenuate GLP-1R-dependentglucose homeostasis in vivo. Diabetes 53(Suppl 3 ):S205-S214, 200414) Mari A, Sallas WM, He YL, et al:Vildagliptin, a dipeptidylpeptidase -Ⅳ inhibitor, improves model -assessed β-cellfunction in patients with type 2 diabetes. J Clin Endo crinolMetab 90:4888-4894, 200515) Hansotia T, Baggio LL, Delmeire D, et al:Double incretinreceptor knockout(DIRKO)Mice reveal an essential rolefor the enteroinsular axis in transducing the glucoregulatoryactions of DPP-Ⅳ inhibitors. Diabetes 53:1326-1335, 200416) Nauck MA, Heimesaat MM, Orskov C, et al:Preservedincretin activity of glucagon-like peptide 1[7-36 amide]but not of synthetic human gastric inhibitory polypeptide inpatients with type -2 diabetes mellitus. J Clin Invest 91:301-307, 199317) Baggio L, Drucker DJ:Biology of incretins:GLP-1 and GIP.Gastroenterology 132:2131-2157, 200718) Waget A, Cabou C, Masseboeuf M, et al:Physiological andpharmacological mechanisms through which the DPP -4inhibitor sitagliptin regulates glycemia in mice. Endocrinology152:3018-3029, 201119) Lamers D, Famulla S, Wronkowitz N, et al:Dipeptidyl peptidase4 is a novel adipokine potentially linking obesity to themetabolic syndrome. Diabetes 60:1917-1925, 2011