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心不全治療の最前線参考文献1）Durrani S, Konoplyannikov M, Ashraf M, et al：Skeletalmyoblasts for cardiac repair. Regen Med 5：919-932, 20102）Menasche P, Alfieri O, Janssens S, et al：The MyoblastAuto....

心不全治療の最前線参考文献1）Durrani S, Konoplyannikov M, Ashraf M, et al：Skeletalmyoblasts for cardiac repair. Regen Med 5：919-932, 20102）Menasche P, Alfieri O, Janssens S, et al：The MyoblastAutologous Grafting in Ischemic Cardiomyopathy（MAGIC）trial：first randomized placebo-controlled study of myoblasttransplantation. Circulation 117：1189-1200, 20083）Sawa Y, Miyagawa S, Sakaguchi T, et al：Tissue engineeredmyoblast sheets improved cardiac function sufficiently to discontinueLVAS in a patient with DCM：report of a case.Surg Today 42：181 -184, 20124）Strauer BE, Brehm M, Zeus T, et al：Repair of infarctedmyocardium by autologous intracoronary mononuclear bonemarrow cell transplantation in humans. Circulation 106：1913 -1918, 20025）Assmus B, Schachinger V, Teupe C, et al：Transplantationof Progenitor Cells and Regeneration Enhancement in AcuteMyocardial Infarction（TOPCARE-AMI）. Circulation 106：3009 -3017, 20026）Schachinger V, Erbs S, Elsasser A, et al：Intracoronary bonemarrow-derived progenitor cells in acute myocardial infarction.N Engl J Med 355：1210-1221, 20067）Jeevanantham V, Butler M, Saad A, et al：Adult bone marrowcell therapy improves survival and induces long-termimprovement in cardiac parameters：a systematic reviewand meta -analysis. Circulation 126：551-568, 20128）Fischer -Rasokat U, Assmus B, Seeger FH, et al：A pilot trialto assess potential effects of selective intracoronary bonemarrow -derived progenitor cell infusion in patients withnonischemic dilated cardiomyopathy：final 1-year results ofthe transplantation of progenitor cells and functional regenerationenhancement pilot trial in patients with nonischemicdilated cardiomyopathy. Circ Heart Fail 2：417 -423, 20099）Sant’anna RT, Kalil RA, Pretto Neto AS, et al：Global contractilityincrement in nonischemic dilated cardiomyopathyafter free wall -only intramyocardial injection of autologousbone marrow mononuclear cells：an insight over stem cellsclinical mechanism of action. Cell Transplant 19：959-964,201010）Choi YH, Kurtz A, Stamm C：Mesenchymal stem cells forcardiac cell therapy. Hum Gene Ther 22：3-17, 201111）Hare JM, Fishman JE, Gerstenblith G, et al：Comparison ofallogeneic vs autologous bone marrow?derived mesenchymalstem cells delivered by transendocardial injection in patientswith ischemic cardiomyopathy：the POSEIDON randomizedtrial. JAMA 308：2369 -2379, 201212）Huang XP, Sun Z, Miyagi Y, et al：Differentiation of allogeneicmesenchymal stem cells induces immunogenicity andlimits their long-term benefits for myocardial repair. Circulation122：2419-2429, 201013）Hatzistergos KE, Quevedo H, Oskouei BN, et al：Bone marrowmesenchymal stem cells stimulate cardiac stem cell proliferationand differentiation. Circ Res 107：913-922, 201014）Williams AR, Hatzistergos KE, Addicott B, et al：Enhancedeffect of human cardiac stem cells and bone marrow mesenchymalstem cells to reduce infarct size and to restore cardiacfunction after myocardial infarction. Circulation 127：213 -223, 201315）Houtgraaf JH, den Dekker WK, van Dalen BM, et al：Firstexperience in humans using adipose tissue -derived regenerativecells in the treatment of patients with ST -segment elevationmyocardial infarction. J Am Coll Cardiol 59：539 -540,201216）Bearzi C, Rota M, Hosoda T, et al：Human cardiac stem cells.Proc Natl Acad Sci U S A 104：14068-14073, 200717）Bolli R, Chugh AR, D’Amario D, et al：Cardiac stem cells inpatients with ischaemic cardiomyopathy（SCIPIO）：initialresults of a randomised phase 1 trial. Lancet 378：1847 -1857,201118）Bolli R, Chugh A, D’Amario D, et al：Effect of cardiac stemcells in patients with ischemic cardiomyopathy：interimresults of the SCIPIO trial up to 2 years after therapy. Circulation126：2784, 201219）Makkar RR, Smith RR, Cheng K, et al：Intracoronary cardiosphere-derivedcells for heart regeneration after myocardialinfarction（CADUCEUS）：a prospective, randomised phase1 trial. Lancet 379：895-904, 201220）Li Q, Guo Y, Ou Q, et al：Intracoronary administration of cardiacstem cells in mice：a new, improved technique for celltherapy in murine models. Basic Res Cardiol 106：849-864,2011Current Therapy 2013 Vol.31 No.441163