カレントテラピー　30-11　サンプル page 21/36

このページは カレントテラピー　30-11　サンプル の電子ブックに掲載されている21ページの概要です。
秒後に電子ブックの対象ページへ移動します。
「電子ブックを開く」をクリックすると今すぐ対象ページへ移動します。

概要：
脳卒中治療研究の最前線神経疾患のリハビリテーションにパラダイムシフトを生み出すものと考えている．再生医療は従来医療従事者，患者や家族が感じてきた限界を打ち破る新たな治療法になり得る可能性を十分に秘めて....

脳卒中治療研究の最前線神経疾患のリハビリテーションにパラダイムシフトを生み出すものと考えている．再生医療は従来医療従事者，患者や家族が感じてきた限界を打ち破る新たな治療法になり得る可能性を十分に秘めている．参考文献1）Akiyama Y, Radtke C, Honmou O, et al：Remyelination ofthe spinal cord following intravenous delivery of bone marrowcells. Glia 39：229-236, 20022）Honma T, Honmou O, Iihoshi S, et al：Intravenous infusionof immortalized human mesenchymal stem cells protectsagainst injury in a cerebral ischemia model in adult rat. ExpNeurol 199：56 -66, 20063）Horita Y, Honmou O, Harada K, et al：Intravenous administrationof glial cell line -derived neurotrophic factor gene -modified human mesenchymal stem cells protects againstinjury in a cerebral ischemia model in adult rat. J NeurosciRes 84：1495-1504, 20064）Iihoshi S, Honmou O, Houkin K, et al：A therapeutic windowfor intravenous administration of autologous bone marrowafter cerebral ischemia in the adult rats. Brain Res 1007：1 -9, 20045）Inoue M, Honmou O, Oka S, et al：Comparative analysis ofremyelinating potential of focal and intravenous administrationof autologous bone marrow cells into the rat demyelinatedspinal cord. Glia 44：111-118, 20036）Kim S, Honmou O, Kato K, et al：Neural differentiationpotential of peripheral blood-and bone marrow-derived precursorcells. Brain Res 1123：27 -33, 20067）Komatsu K, Honmou O, Suzuki J, et al：Therapeutic timewindow of mesenchymal stem cells derived from bone marrowafter cerebral ischemia. Brain Res 1334：84-92, 20108）Liu H, Honmou O, Harada K, et al：Neuroprotection by PlGFgene -modified human mesenchymal stem cells after cerebralischemia. Brain 129：2734-2745, 20069）Nakamura K, Ito Y, Kawano Y, et al：Antitumor effect ofgenetically engineered mesenchymal stem cells in a rat gliomamodel. Gene Ther 11：1155 -1164, 200410）Nomura T, Honmou O, Harada H, et al：I.v. infusion ofbrain -derived neurotrophic factor gene -modified humanmesenchymal stem cells protects against injury in a cerebralischemia model in adult rat. Neuroscience 136：161-169, 200511）Omori Y, Honmou O, Harada K, et al：Optimization of atherapeutic protocol for intravenous injection of human mesenchymalstem cells after cerebral ischemia in adult rats.Brain Res 1236：30-38, 200812）Onda T, Honmou O, Harada K, et al：Therapeutic benefitsby human mesenchymal stem cells（hMSCs）and Ang -1gene-modified hMSCs after cerebral ischemia. J Cereb BloodFlow Metab 28：329-340, 200813）Toyama K, Honmou O, Harada K, et al：Therapeutic benefitsof angiogenetic gene -modified human mesenchymal stemcells after cerebral ischemia. Exp Neurol 216：47-55, 200914）Ukai R, Honmou O, Harada K, et al：Mesenchymal stem cellsderived from peripheral blood protects against ischemia. JNeurotrauma 24：508 -520, 200715）Zheng W, Honmou O, Harada K, et al：Therapeutic benefitsof human mesenchymal stem cells derived from bone marrowafter global cerebral ischemia. Brain Res 1310：8 -16,200916）Honmou O, Houkin K, Matsunaga T, et al：Intravenousadministration of auto serum -expanded autologous mesenchymalstem cells in stroke. Brain 134：1790-1807, 201117）Song CH, Honmou O, Ohsawa N, et al：Effect of transplantationof bone marrow -derived mesenchymal stem cells onmice infected with prion. J Virol 83：5918-5927, 200918）Honmou O, Houkin K：Stem cell therapy for cerebral ischemia.No Shinkei Geka 38：515 -520, 201019）Sasaki M, Honmou O, Akiyama Y, et al：Transplantation ofan acutely isolated bone marrow fraction repairs demyelinatedadult rat spinal cord axons. Glia 35：26-34, 200120）Sasaki M, Radtke C, Tan AM, et al：BDNF-hypersecretinghuman mesenchymal stem cells promote functional recovery,axonal sprouting, and protection of corticospinal neuronsafter spinal cord injury. J Neurosci 29：14932-14941, 2009Current Therapy 2012 Vol.30 No.11117171